Publications

Nombela, P., Miguel-López, B. & Blanco, S. The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities. Mol Cancer 20, 18 (2021). https://doi.org/10.1186/s12943-020-01263-w

Mario Delgado, María Moros, Raúl V Durán, Xosé R Bustelo, M Ángela Nieto, Joaquín Arribas, Sandra Blanco, et al. “Challenges in Biomedicine and Health”. Libro Blanco CSIC 4 (2020). Publisher Consejo Superior de Investigaciones Científicas (España). Doi: http://dx.doi.org/10.20350/digitalCSIC/12651.

Sevilla A, Bernaus A, Blanco S. Glia Crosstalk in Neuroinflammatory Diseases. Frontiers in Cellular Neuroscience. 2020 Jul 29;14:209. doi: 10.3389/fncel.2020.00209. eCollection 2020.

Rosace D, López J, Blanco S. Emerging roles of novel small non-coding regulatory RNAs in immunity and cancer. RNA Biology. 2020 Mar 18:1-18. doi: 10.1080/15476286.2020.1737442.

Janin M, Ortiz V, Castro de Moura M, Martínez-Cardús A, Llinàs-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno A, De La Torre C, Villanueva A, Thomas G, Blanco S, Seoane J, Preiss T, Pandolfi PP, Esteller M. Epigenetic Loss of the RNA Methyltransferase NSUN5 Targets 28S Ribosomal RNA and Drives a Stress-Survival Translational Program in Human Gliomagenesis. Acta Neuropathol. 2019 Aug 19. 138(6):1053-1074. doi: 10.1007/s00401-019-02062-4.

Gkatza NA, Castro C, Popis MC, Blanco S, Bornelöv S, Gleeson J, Griffin JL, West JA, Kellner S, Dietmann S, Frye M. Cytosine-5 RNA methylation links protein synthesis to cell metabolism. PLoS Biology. 2019 Jun 14;17(6):e3000297. doi: 10.1371/journal.pbio.3000297. eCollection 2019 Jun.

García-Vílchez R, Sevilla A and Blanco S. Post-transcriptional regulation by cytosine-5 methylation of RNA. Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):240-252. doi:10.1016/j.bbagrm.2018.12.003.

Davalos V*, Blanco S*, Esteller M. SnapShot: Messenger RNA Modifications. Cell. 2018 Jul 12;174(2):498-498.e1. doi: 10.1016/j.cell.2018.06.046. *Equal contribution.

Popis MC, Wagner RE, Contantino-Casas F, Blanco S, Frye F. Considerations for skin carcinogenesis experiments using inducible transgenic mouse models. BMC Res Notes. 2018 Jan 24;11(1):67. doi: 10.1186/s13104-018-3182-3.

Flores JV, Cordero-Espinoza L, Oeztuerk-Winder F, Andersson-Rolf A, Selmi T, Blanco S, Tailor J, Dietmann S, Frye M. Cytosine-5 RNA methylation regulates neural stem cell differentiation and motility. Stem Cell Reports. 2017 Jan 10;8(1):112-124. doi: 10.1016/j.stemcr.2016.11.014.

Frye M and Blanco S.  Post-transcriptional modifications of RNA in development and stem cell self-renewal and differentiation. Development. 2016 Nov 1;143(21):3871-3881. DOI: 10.1242/dev.136556.

Van Haute L, Dietmann S, Kremer L, Hussain S, Pearce SF, Powell CA, Rorbach J, Lantaff R, Blanco S, Sauer S, Kotzaeridou U, Hoffmann GF, Memari Y, Kolb-Kokocinski A, Durbin R, Mayr JA, Frye M, Prokisch H, Minczuk M. Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3. Nat Commun. 2016 Jun 30;7:12039. doi: 10.1038/ncomms12039.

Blanco S, Bandiera R, Popis MC, Hussain S, Lombard P, Aleksic J, Sajini A, Cortés-Garrido R, Tanna H, Gkatza N, Dietmann S, Frye M. Stem cell function and stress response are controlled by protein synthesis. Nature Research Article. 2016 Jun 16;534(7607):335-40. doi: 10.1038/nature18282.

Blanco S, Popis M, Frye M. Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer. Curr Opin Oncol. 2016 Jan; 28(1):65-71. doi: 10.1097/CCO.0000000000000252.

Satterlee J, Basanta-Sanchez M, Blanco S, Billy Li J, Meyer K, Pollock J, Sadri-Vakili G and Rybak-Wolf A. Novel RNA Modifications in the Nervous System: Form and Function. J Neuroscience. 2014 Nov 12;34(46):15170-7. doi: 10.1523/JNEUROSCI.3236-14.2014.

Blanco S, Dietmann S, Flores JV, Hussain S, Kutter C, Humphreys P, Lukk M, Lombard P, Treps L, Popis M, Kellner S, Hölter SM, Garrett L, Wurst W, Becker L, Klopstock T, Fuchs H, Gailus-Durner V, Hrabĕ de Angelis M, Káradóttir RT, Helm M, Ule J, Gleeson JG, Odom DT, Frye M. Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J. 2014 Sept 17; 33(18):2020-39. doi: 10.15252/embj.201489282.

Blanco S, Frye M. Role of RNA methyltransferases in tissue renewal and pathology. Curr Opin Cell Biol. 2014 Dec; 31C:1-7. doi: 10.1016/j.ceb.2014.06.006.

Hussain S, Aleksic J, Blanco S, Dietmann S, Frye M. Characterizing 5-methylcytosine in the mammalian epitranscriptome. Genome Biol. 2013 Nov; 14(11):215. doi: 10.1186/gb4143.

Hussain S, Sajini AA, Blanco S, Dietmann S, Lombard P, Sugimoto Y, Paramor M, Gleeson JG, Odom DT, Ule J, Frye M. NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs. Cell Rep. 2013 Jul; 4(2):255-61. doi: 10.1016/j.celrep.2013.06.029.

Hussain S, Tuorto F, Menon S, Blanco S, Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M. The Mouse Cytosine-5 RNA Methyltransferase NSun2 Is a Component of the Chromatoid Body and Required for Testis Differentiation. Mol Cell Biol. 33(8):1561-70. doi: 10.1128/MCB.01523-12.

Martinez FJ, Lee JH, Lee JE, Blanco S, Nickerson E, Gabriel S, Frye M, Al-Gazali L, Gleeson JG. Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome. J Med Genet. 2012 Jun; 49(6):380-5. doi: 10.1136/jmedgenet-2011-100686.

Blanco S, Kurowski A, Nichols J, Watt FM, Benitah SA, Frye M. The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet. 2011 Dec; 7(12):e1002403 doi: 10.1371/journal.pgen.1002403.